New publication in the prestige “Journal of Arthroplasty” demonstrates that Using an IPCD and TXA and discontinuing enoxaparin and preoperative autologous blood donation eliminated blood transfusion in primary THA and TKA without any increase in VTED. Using an IPCD instead of enoxaparin, adding TXA, and eliminating preoperative autologous donation each had an incremental dose response effect. This protocol provides effective VTED prophylaxis equivalent to pharmacologic methods and eliminates transfusion risk in the primary THA and TKA population.

Study title: Balancing Thromboprophylaxis and Bleeding in Total Joint Arthroplasty: Impact of Eliminating Enoxaparin and Predonation and Implementing Pneumatic Compression and Tranexamic Acid.

Zachary T. Sharfman, MScorrespondence, Joshua C. Campbell, MD, James M. Mirocha, MS, Andrew I. Spitzer, MD

Department of Orthopaedic Surgery, Cedars-Sinai Medical Center, Los Angeles, California.

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